Table 2.
STAT3-Regulated Genes Altered in Response to Combined EAF2 and p53 Knockdown in C4-2 Prostate Cancer Cells Identified by IPA
| Gene | HUGO* Gene Name | Fold-Change (siCont:siDouble) |
|---|---|---|
| ARG2 | arginase 2 | 0.430074586 |
| BST2 | bone marrow stromal cell antigen 2 | 2.741465156 |
| CCL5 | C-C motif chemokine ligand 5 | 12.95052 |
| CDKN1A | cyclin dependent kinase inhibitor 1A | 0.299638 |
| CEBPB | CCAAT/enhancer binding protein beta | 2.110388 |
| CXCL10 | C-X-C motif chemokine ligand 10 | 46.08148 |
| DDIT3 | DNA-damage inducible transcript 3 | 2.10529 |
| GBP2 | guanylate binding protein 2 | 5.109627 |
| IFI27 | interferon alpha inducible protein 27 | 4.871708 |
| IFI44 | interferon induced protein 44 | 3.399659 |
| IFI6 | interferon alpha inducible protein 6 | 7.756538586 |
| IFIT1 | interferon induced protein with tetratricopeptide repeats 1 | 20.14326215 |
| IFIT2 | interferon induced protein with tetratricopeptide repeats 2 | 24.6528095 |
| IFIT3 | interferon induced protein with tetratricopeptide repeats 3 | 30.08867001 |
| IFITM1 | interferon induced transmembrane protein 1 | 20.05318114 |
| IL4R | interleukin 4 receptor | 0.448043593 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1 | 4.805611452 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2 | 44.93395535 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3 | 2.159541374 |
| OASL | 2'-5'-oligoadenylate synthetase like | 73.02252524 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase | 0.479701624 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 9.931982035 |
| SP110 | SP110 nuclear body protein | 2.157420835 |
| TP53 | Tumor protein 53 | 0.393462413 |