Table 2. (A). Plasma and Red Cell Phospholipid and Adipose Tissue Fatty Acid Composition.

Fatty Acid		Pre	Post	P-value	Pre	Post	P-value
Linoleic acid	C18:2	21.27 (3.82)	21.38 (1.4)	0.77	14.87 (2.5)	14.59 (2.73)	0.56
Alpha linoleic acid		0.22 (0.09)	0.25 (0.05)	0.32	0.21 (0.1)	0.21 (0.07)	0.37
Dihomo-gamma-linoleic acid
	C20:3n-6	3.34 (1.52)	2.6 (0.91)	0.004*	1.66 (0.8)	1.55 (0.4)	0.004*
Arachidonic acid	C20:4	14.1 (5.63)	11.13 (3.1)	0.004*	15.51 (2.98)	13.15 (1.98)	0.002*
Eicosapentaenoic acid	C20:5n-3	0.57 (0.37)	1.13 (0.21)	0.002*	0.55 (0.23)	0.9 (0.23)	0.002*
Adrenic acid	C22:4n-6	0.48 (0.16)	0.24 (0.06)	0.002*	3.73 (0.23)	2.46 (0.29)	0.002*
Docosapentaenoic acid	C22:5n-3	0.8 (0.06)	0.4 (0.11)	0.002*	2.06 (0.47)	1.15 (0.26)	0.002*
Docosahexaenoic acid	C22:6n-3	2.96 (0.84)	8.48 (2.13)	0.002*	4.11 (1.24)	9.3 (1.46)	0.002*
Omega6		41.08 (0.88)	35.62 (2.25)	0.002*	36.62 (1.19)	33.15 (3.7)	0.004*
Omega3		4.71 (0.99)	10.0 (1.6)	0.002*	6.76 (2.17)	11.46 (1.22)	0.002*
Omega6/Omega3 ratio		8.67 (1.83)	3.54 (0.6)	0.002*	5.4 (2.18)	2.93 (0.54)	0.002*

B:
Adipose Tissue
Fatty Acid		Pre	Post	P-value
Linoleic acid	C18:2	19.28 (2.90)	18.91 (3.14)	0.56
Alpha linoleic acid	C18:3 n-3	0.35 (0.66)	0.67 (0.73)	0.38
Dihomo-gamma-linoleic acid	C20:3n-6	0.36 (0.07)	0.34 (0.05)	0.81
Arachidonic acid	C20:4	0.45 (0.19)	0.54 (0.14)	0.51
Eicosapentaenoic acid	C20:5n-3	0.05 (0.03)	0.05 (0.04)	0.39
Adrenic acid	C22:4n-6	0.20 (0.06)	0.22 (0.07)	0.44
Docosapentaenoic acid	C22:5n-3	0.18 (0.06)	0.20 (0.06)	0.47
Docosahexaenoic acid	C22:6n-3	0.13 (0.10)	0.27 (0.09)	0.002*
Omega6		20.78 (3.31)	20.37 (3.15)	0.56
Omega3		0.84 (0.57)	1.11 (0.68)	0.05
Omega6/Omega3 ratio		23.54 (30.19)	17.77 (11.81)	0.04

Data are presented as percent of total fatty acid mass as median (interquartile range)

^*P-values are significant after adjustment for multiple testing using FDR < 5% level