Table 4. Effects of Dha administration on serum analytes.

Glucose (mmol/L)	5.62 (0.7)	5.95 (0.76)	0.001*
AST (units/l)	19.7 (3.5)	22.1 (3.1)	0.04
ALT (units/l)	16.8 (4.6)	19.8 (6.8)	0.05
Prothrombin time (sec)	11.0 (0.7)	10.7 (0.7)	0.02
PTT (sec)	30.5 (3.4)	30.3 (3.2)	0.03
Estradiol (ng/L)	14.3 (7.6)	14.4 (7.0)	0.89
Testosterone (nmol/L)	0.59 (0.30)	0.55 (0.17)	0.62
Inflammatory Markers Hs CRP (mg/dl)
	0.5 (0.4)	0.4 (0.3)	0.37
IL-6 (pg/ml)	1.7 (0.4)	1.5 (0.7)	0.66
IL-8 (pg/ml)	11.1 (3.6)	9.4 (2.0)	0.14
TNF-a (pg/ml)	14.8 (3.2)	13.9 (1.6)	0.48
IL-10 (pg/ml)	3.1 (2.0)	2.9 (1.8)	0.77

Data pre and post DHA administration shown as mean (+/- SD) in 10 subjects. Inflammatory markers measured in 5 subjects.

^*P-value is significant after adjustment for multiple testing using FDR < 5% level

AST = aspartate aminotransferase ALT = alanine transaminase PTT = partial thromboplastin time

hs CRP = high sensitivity C-reactive protein IL = interleukin

TNF a = tumor necrosis factor alpha