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. Author manuscript; available in PMC: 2018 Apr 20.
Published in final edited form as: Lancet Neurol. 2015 Apr;14(4):388–405. doi: 10.1016/S1474-4422(15)70016-5

Figure 4. Impact of amyloid β on microglia.

Figure 4

Aβ aggregates (oligomers) act on several TLR receptors on the microglial surface provoking reactions of the innate immune system. On the other side Aβ oligomers are internalized by microglia by the help of the the scavanger receptor A1 (SR-A1), α6β1-integrins, CD36 and CD47.