Table 2.
Dietary Modulation of the Blood Metabolome
| Sample | Metabolites Identified by Platform
|
|||
|---|---|---|---|---|
| GC-MS | LC-MS | NMR | Other* | |
|
| ||||
| Blood | Betaine | Butyrylcarnitine | B-hydroxybutyrate | Caffeic Acid |
| N-dimethylglycine | L-tryptophan | Lactate | Sulphonatemethylepicatechin | |
| Dimethyl sulfone | Choline | Acetate | ||
| Stearic Acid | Cysteine | Betaine/trimethylamine-N-oxide | ||
| Oleic Acid | Glycine | Glycine betaine | ||
| LysoPC 14:0 | Methionine | β-glucose | ||
| LysoPC 18:0 | Serine | α-glucose | ||
| LysoPC 18:1 | Urate | inosine/adenosine and nucleotides | ||
| LysoPC 18:2 | Phenylalanine | Campesterol | ||
| LysoPC 20:2 | Alanine | DHA | ||
| L-Carnitine | Histidine | Cholestenol | ||
| L-Valine | Branched-chain amino acids | Sphingosine moiety | ||
| D-Pipecolic acid | Isobutyrate | Nervonic acid | ||
| L-Tyrosine | Palmitic acid | Erythrosphingosine | ||
| L-Leucine | EPA | Threosphingosine | ||
| Propionylcarnitine | Cholic acid | 3-O-methylsphingosine | ||
| SIRT1 | Saccharic acid | 5-O-methylsphingosine | ||
| 11-dehydro thromboxane B (2) | Sucrose | N-methylalanine | ||
| 3-hydroxybutanoic acid | γ-linoleic acid | palmitoleic acid | ||
| Sulfoglycolithocholic acid | Phenylacetylglutamine | 3-hydroxy-3-methylglutaric acid | ||
| Threitol | Tryptophan | Idonic acid | ||
| Hydrocinnamic acid | Taurine | Lactobionic acid | ||
| α-ketoglutaric acid | Citric Acid | 3-phenyllactic acid | ||
| Docosapentaenoic acid | L-proline | Glycerol-3-galactoside | ||
| O-acetylcarnitine | α-tocopherol | Raffinose | ||
| Proline | Betasitosterol | Actetoacetate | ||
| Tyrosine | Urolithin A glucuronide | Glucose | ||
| Carnitine | Niacine | Creatinine | ||
| SIRT1 | Biuret | Triacylglycerol | ||
| Creatine | Glycerol | |||
| Oleic Acid | Ascorbic acid | |||
| Hippuric Acid | urolithin C (trihydroxydibenzopyranone) | |||
| Adenine | Acetone | |||
| LysoPC | ||||
| Uric Acid | ||||
| Creatinine | ||||
| Leucine | ||||
| Putrescine | ||||
|
| ||||
| References | [2, 38, 59, 70–72] | [38, 40, 59, 61, 73–76] | [11, 20, 21] | [1, 67, 71] |
*
Other Platforms used in Identifying Metabolites: ICP-OES: Inductively Coupled Plasma Spectroscopy, DAD-MS/MS: Diode Array Detector Mass Spectrometry, FIEI-MS: Flow Injection Electrospray-ionisation.