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. 2017 Aug 18;10(5):434–439. doi: 10.1136/neurintsurg-2017-013233

Table 2.

Procedure Time

Procedure and outcome All patients, (n=58) Isolated M2 or M3 (n=31) LVO+M2 or M3 (n=27) Difference (95% CI)* p Value
Time from symptom onset to groin puncture (median, IQR), min 105 (95–120) 105 (95–125) 110 (95–120) 0 (−10 to 10) 0.9563
Time from symptom onset to recanalization (median, IQR), min 130 (115–145) 127.5 (115–145) 130 (115–150) 0 (−15 to 10) 0.6646
Procedure duration (median, IQR), min 54.3 (37–65) 45.3 (30–55) 63.5 (45–75) −22 (−40 to 5) 0.014
Post-treatment mTICI score 2b–3 (n/N (%)), per core laboratory 58/58 (100%) 31/31 (100%) 27/27 (100%) 0%, N/A 1.0000
Post-treatment mTICI score 2b–3 (n/N (%)), per site PI 53/58 (91.4%) 28/31 (90.3%) 25/27 (92.6%) −2.3% (−27.4% to 23.4%) 1.0000
Post-treatment mTICI score 3 (n/N (%)), per core laboratory 48/58 (82.8%) 24/31 (77.4%) 24/27 (88.9%) −11.5% (−36.4% to 14.1%) 0.3110
Post-treatment mTICI score 3 (n/N (%)), per site PI 41/58 (70.7%) 22/31 (71.0%) 19/27 (70.4%) 1.0% (−25.0% to 26.1%) 1.0000
Post-treatment NIHSS score (median, IQR) 4 (3–6) 4 (3–5) 5 (3–7) −1 (−2 to 0) 0.1909
Good functional outcome at discharge, mRS 0–2 (n/N (%)) 54/58 (93.1%) 29/31 (93.5%) 25/27 (92.6%) 1.0% (−24.3% to 26.5%) 1.0000
Good functional outcome at 90 days, mRS 0–2 (n/N (%)) 55/58 (94.8%) 30/31 (96.8%) 25/27 (92.6%) 4.2% (−21.3% to 29.6%) 0.5931
Symptomatic ICH (n/N (%)) 2/58 (3.4%) 0/31 (0%) 2/27 (7.4%) −7.4% (−32.6% to 18.3%) 0.2123
Asymptomatic ICH (n/N (%)) 10/58 (17.2%) 2/31 (6.5%) 8/27 (29.6%) −23.2% (−46.6% to 3.0%) 0.0340
Vessel dissection (n/N (%)) 0/58 (0%) 0/31 (0%) 0/27 (0%) 0%, N/A 1.000
Vessel perforation (n/N (%)) 0/58 (0%) 0/31 (0%) 0/27 (0%) 0%, N/A 1.000
Major groin complication (n/N (%)) 0/58 (0%) 0/31 (0%) 0/27 (0%) 0%, N/A 1.000

*Wilcoxon rank sum or Fisher’s exact test for difference between isolated M2 or M3 and LVO + M2 or M3 groups. Hodges-Lehmann estimate and CI was computed for results of Wilcoxon rank sum test. Exact estimate and Clopper-Pearson CI was computed for results of Fisher’s exact test.

ICH, intracranial hemorrhage; LVO, large vessel occlusion; mRS, modified Rankin Scale; mTICI, modified Thrombolysis in Cerebral Infarction; NIHSS, National Institutes of Health Stroke Scale; PI, Principal Investigator.