Table 4.

Most common differential diagnoses for intertriginous dermatitis on skin-fold areas

Differential diagnosis	Anatomical sites of candidal infection
	Large skin folds (axilla, inframammary, umbilical, intergluteal, and genitocrural)	Diaper intertrigo	EIB	Toe web intertrigo	Perianal and perineal intertrigo	intertrigo of the neck folds	Eyelids and retroauricular
Atopic dermatitis		√
Bacterial intertrigo	√	√	√	√	√	√	√
Bullous impetigo		√
Contact dermatitis	√	√	√	√	√	√	√
Dermatophyte infections	√	√	√	√	√	√
Drug interaction	√
Erythrasma	√	√	√	√	√
Extramammary Paget disease	√				√
Flexural Darier disease	√					√
Fusarium spp. infections				√
Glucagonoma	√					√
Granular parakeratosis	√
Hailey disease	√				√	√
Herpes infections		√	√		√		√
HPV infections			√	√	√
Langerhans cell histiocytosis		√			√
Leiner disease	√	√			√	√	√
Lichen planus inversus	√
Multiple carboxylase deficiency		√
Psoriasis	√	√		√	√	√
Seborrheic dermatitis	√	√			√	√	√
Syphilis	√	√			√	√
Verrucous carcinoma	√			√
Zinc deficiency/acrodermatitis enteropathica	√	√		√	√	√

Note: Data taken from several studies.²,⁷,⁹,¹⁰,²⁸,²⁹,³¹,⁴⁷,⁴⁹–⁵¹,⁵⁸,⁶²–⁶⁴,⁶⁷,⁶⁹,⁷⁰,⁷²–⁷⁷,⁸⁴,⁹⁶–¹⁰³

Abbreviations: HPV, human papillomavirus; EIB, Erosio interdigitalis blastomycetica