Table 1.
Baseline Characteristics of Enrolled Patients, by Group
| Characteristic | Donor FMT (n = 22) | Autologous FMT (n = 24) |
|---|---|---|
| Mean age (SD), y | 48 (16) | 55 (14) |
| Female, n (%) | 18 (82) | 19 (79) |
| Mean body mass index (SD), kg/m2 | 28 (8) | 27 (7) |
| Median Charlson Comorbidity Index score (range) | 1 (0–4) | 0 (0–3) |
| Mean duration of CDI since initial diagnosis (SD) [range], mo | 9 (9) [3–36] | 12 (12) [3–48] |
| Mean CDI recurrences (SD) [range], n | 4 (2) [3–9] | 5 (2) [2–10] |
| Mean duration of oral vancomycin therapy (SD) [range], wk* | 28 (36) [6–140] | 23 (30) [8–148] |
| Prior probiotic treatment, n (%) | 15 (68) | 18 (75) |
| Prior Lactobacillus GG use, n (%) | 5 (23) | 3 (13) |
| Prior Saccharomyces boulardii use, n (%) | 11 (50) | 13 (54) |
| Prior rifaximin use, n (%) | 3 (13) | 1 (4) |
| Prior fidaxomicin use, n (%) | 6 (27) | 8 (33) |
| Proton-pump inhibitor use, n (%) | 2 (9) | 2 (8) |
CDI = Clostridium difficile infection; FMT = fecal microbiota transplantation.
For all prior CDI treatment courses combined; does not necessarily represent continuous use.