Table 1.
Disease | Age | MMSE | UPDRS - Total | Disease Duration | Unified Lewy Body Stage | Pilomotor αSN | Sudomotor αSN | Vasomotor αSN |
---|---|---|---|---|---|---|---|---|
Control | 95 | 28 | 8 | 0 | Stage 0 | 1 | 1 | 0 |
Control | 87 | 26 | 1 | 0 | Stage 0 | 0 | 0 | 1 |
Control | 81 | 29 | 5 | 0 | Stage 0 | 2 | 0 | 1 |
Control | 68 | 29 | 3 | 0 | Stage 0 | 0 | 1 | 0 |
Control | 75 | 29 | 2 | 0 | Stage 0 | 0 | 1 | 2 |
PD | 87 | 13 | 57 | 21 | Stage 4- Neocortical | 0 | 2 | 1 |
PD | 75 | 27 | 32 | 20 | Stage 3- Brainstem/Limbic | 2 | 1 | 3 |
PD | 81 | 19 | 74 | 14 | Stage 3- Brainstem/Limbic | 3 | 0 | 2 |
PD | 79 | 29 | 38 | 14 | Stage 3- Brainstem/Limbic | 2 | 1 | 3 |
PD | 69 | 24 | 21 | 10 | Stage 3- Brainstem/Limbic | 1 | 2 | 2 |
PD | 91 | 26 | 17 | 12 | Stage 3- Brainstem/Limbic | 2 | 2 | 1 |
PD | 75 | 26 | 27 | 21 | Stage 4- Neocortical | 3 | 0 | 3 |
PD | 74 | 27 | 51 | 17 | Stage 3- Brainstem/Limbic | 3 | 2 | 2 |
PD | 78 | 24 | 51 | 19 | Stage 3- Brainstem/Limbic | 2 | 3 | 3 |
PD | 75 | N/A | 17 | 20 | Stage 4- Neocortical | 0 | 2 | 3 |
PD | 84 | N/A | 28 | 20 | Stage 3- Brainstem/Limbic | 2 | 2 | 1 |
MMSE: mini mental status examination, UPDRS: Unified Parkinson’s Disease Rating Scale, Unified Lewy Body Stage: Scale of 0 (none) to 4 (neocortical involvement). Pilomotor ASN: scoring of alpha synuclein deposition within pilomotor nerves (0-4 scale). Sudomotor ASN: Sudomotor alpha synuclein deposition within sudomotor nerves (0-4 scale).