Table II.
Top 10 DEGs.
| Comparison | Symbol | Description | Fold change | P-value |
|---|---|---|---|---|
| TL vs TNL | TNFAIP3 | tumour necrosis factor, alpha-induced protein 3 | 2.716 | 1.40E–04 |
| IER3 | immediate early response 3 | 2.68 | 2.37E–03 | |
| IL-6 | interleukin 6 | 2.657 | 8.79E–03 | |
| PTGS2 | prostaglandin-endoperoxide synthase 2 | 2.474 | 2.15E–03 | |
| ATF3 | activating transcription factor 3 | 2.31 | 6.30E–03 | |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 2.147 | 3.98E–03 | |
| DUSP5 | dual specificity phosphatase 5 | 2.066 | 3.64E–03 | |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 1.988 | 8.04E–04 | |
| ZC3H12A | zinc finger CCCH-type containing 12 A | 1.905 | 3.84E–03 | |
| DDIT4 | DNA-damage-inducible transcript 4 | 1.824 | 4.79E–03 | |
| MMP7 | matrix metallopeptidase 7 (matrilysin, uterine) | −2.387 | 1.84E–03 | |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | −1.564 | 1.51E–05 | |
| COL6A3 | collagen, type VI, alpha 3 | −1.538 | 4.49E–03 | |
| CIRBP | cold inducible RNA binding protein | −1.456 | 1.88E–03 | |
| NID1 | nidogen 1 | −1.396 | 7.91E–03 | |
| CYB561D1 | cytochrome b561 family, member D1 | −1.394 | 2.64E–03 | |
| CLSTN1 | calsyntenin 1 | −1.355 | 9.51E–03 | |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase | −1.338 | 2.94E–03 | |
| RAB22A | RAB22A, member RAS oncogene family | −1.327 | 9.02E–04 | |
| CCDC106 | coiled-coil domain containing 106 | −1.303 | 6.30E–03 | |
| TL vs PTL | FOSB | FBJ murine osteosarcoma viral oncogene homologue B | 2.538 | 9.45E–03 |
| FST | follistatin | 2.325 | 3.96E–03 | |
| HES4 | hes family bHLH transcription factor 4 | 1.691 | 9.09E–04 | |
| KLF4 | Kruppel-like factor 4 (gut) | 1.563 | 9.62E–03 | |
| SASH1 | SAM and SH3 domain containing 1 | 1.493 | 8.10E–03 | |
| HRK | harakiri, BCL2 interacting protein | 1.492 | 9.84E–03 | |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 1.489 | 5.24E–03 | |
| ELMSAN1 | ELM2 and Myb/SANT-like domain containing 1 | 1.44 | 2.50E–03 | |
| FOXC1 | forkhead box C1 | 1.418 | 4.11E–03 | |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | 1.414 | 6.07E–03 | |
| FGA | fibrinogen alpha chain | −4.108 | 6.28E–03 | |
| FGG | fibrinogen gamma chain | −3.688 | 5.88E–04 | |
| FGB | fibrinogen beta chain | −2.753 | 2.53E–03 | |
| PLAT | plasminogen activator, tissue | −2.235 | 5.73E–03 | |
| MARCO | macrophage receptor with collagenous structure | −2.087 | 4.03E–03 | |
| LILRA3 | leucocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 | −1.945 | 9.45E–03 | |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 | −1.769 | 8.67E–03 | |
| KCNK4 | potassium channel, subfamily K, member 4 | −1.75 | 1.95E–03 | |
| TNFRSF8 | tumour necrosis factor receptor superfamily, member 8 | −1.72 | 1.53E–03 | |
| WARS | tryptophanyl-tRNA synthetase | −1.712 | 9.12E–03 | |
| PTL vs PTNL | CXCL8 | chemokine (C-X-C motif) ligand 8 | 5.441 | 2.49E–03 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 3.338 | 6.97E–03 | |
| S100A8 | S100 calcium binding protein A8 | 3.193 | 1.02E–03 | |
| FGG | fibrinogen gamma chain | 3.023 | 3.76E–03 | |
| SOD2 | superoxide dismutase 2, mitochondrial | 2.89 | 2.04E–03 | |
| FGB | fibrinogen beta chain | 2.784 | 3.08E–03 | |
| NAMPT | nicotinamide phosphoribosyltransferase | 2.742 | 1.03E–03 | |
| FGG | fibrinogen gamma chain | 2.687 | 9.45E–04 | |
| S100A9 | S100 calcium binding protein A9 | 2.547 | 9.93E–04 | |
| AQP9 | aquaporin 9 | 2.528 | 3.60E–03 | |
| FOSB | FBJ murine osteosarcoma viral oncogene homologue B | −2.652 | 8.73E–03 | |
| TACSTD2 | tumour-associated calcium signal transducer 2 | −2.334 | 9.47E–03 | |
| MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase | −1.702 | 2.04E–03 | |
| SASH1 | SAM and SH3 domain containing 1 | −1.536 | 6.36E–03 | |
| CYB561D1 | cytochrome b561 family, member D1 | −1.467 | 1.96E–03 | |
| FAM53B | family with sequence similarity 53, member B | −1.448 | 5.53E–03 | |
| CRYZ | crystallin, zeta (quinone reductase) | −1.438 | 9.11E–03 | |
| C22orf29 | chromosome 22 open reading frame 29 | −1.436 | 2.44E–03 | |
| ZHX3 | zinc fingers and homeoboxes 3 | −1.428 | 2.39E–04 | |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | −1.412 | 1.12E–03 |
DEG, differentially expressed gene.