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. 2018 Apr 20;13(4):e0196182. doi: 10.1371/journal.pone.0196182

Fig 4. Histograms of sampled fluxes of the main sources of NADPH.

Fig 4

Distribution of sampled points from the solution space of each strain under sub-optimal conditions of growth. The histograms of the main sources of NADPH are shown (G6PDH: glucose 6-phosphate dehydrogenase; 6PGDH: 6-phosphogluconate dehydrogenase; ME: malic enzyme; ICDH: isocitrate dehydrogenase; PntAB: membrane-bound transhydrogenase). Simulations were performed using the physiological parameters and a 90% of each growth rate to model the sub-optimal conditions. Also, if the optimal flux was not zero, vertical red lines indicate this value.