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. Author manuscript; available in PMC: 2018 Apr 20.

Published in final edited form as: Toxicology. 2018 Feb 8;396-397:33–45. doi: 10.1016/j.tox.2018.02.003

Fig. 4 — Effects of leflunomide (A) and A77 1726 (B) on the activities of mitochondrial electron transport complexes in isolated bovine heart mitochondria. Data are expressed as mean ± SD (n = 3). The 50% inhibitory concentration (IC₅₀) of leflunomide on Complex I, II, II + III, IV, and V activity were obtained from dose-response curves.

Fig. 4 — Effects of leflunomide (A) and A77 1726 (B) on the activities of mitochondrial electron transport complexes in isolated bovine heart mitochondria. Data are expressed as mean ± SD (n = 3). The 50% inhibitory concentration (IC₅₀) of leflunomide on Complex I, II, II + III, IV, and V activity were obtained from dose-response curves.