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. 2018 Feb 16;67(5):1013–1023. doi: 10.2337/db17-1207

Figure 3.

Figure 3

A: Venn diagram of genes targeted by each of the four candidate miRNAs. The genes were selected as targets if they had overlapped in at least in 6 of 12 prediction algorithms (MicroT4, miRWalk, miRBridge, miRanda, miRDB, miRMap, Pictar2, PITA, miRNAMap, RNAhybrid, RNA22, and TargetScan). B: Venn diagram of pathways enriched with genes targeted by the four candidate miRNAs with P < 0.01. Nineteen pathways related to cancer were eliminated. In the middle of the diagram, there is the axon guidance signaling pathway, which was enriched by genes targeted by all four miRNAs. Other enriched pathways are listed in Table 3 and Supplementary Tables 4 and 5.