Table 3.
Glycemic Outcomes Over the 36-H Hybrid Closed-Loop Phase
| Parameter | Adultsa(n = 24) | Adults (n = 10) | Adolescents (n = 12) | Pediatrics (n = 12) |
|---|---|---|---|---|
| Mean sensor glucose, mg/dL | 161.5 (20.1) | 155.0 (14.8) | 153.4 (21.6) | 156.9 (20.4) |
| Standard deviation, mg/dL | 54.0 | 46.2 | 48.6 | 53.3 |
| Coefficient of variation, % | 33.4 | 29.8 | 31.8 | 34.0 |
| Percentage time in glucose range | ||||
| <54 mg/dL | 0.1 (0.3) | 0.1 (0.3) | 0.2 (0.3) | 0.2 (0.7) |
| <60 mg/dL | 0.2 (0.6) | 0.2 (0.6) | 0.7 (0.9) | 0.6 (1.2) |
| <70 mg/dL | 0.7 (1.7) | 0.7 (1.2) | 2.0 (2.4) | 2.0 (2.6) |
| 70 to 140 mg/dL | 41.5 (18.1) | 41.9 (16.3) | 40.2 (15.5) | 39.4 (16.1) |
| 70 to 180 mg/dL | 69.5 (14.4) | 73.0 (15.0) | 72.6 (15.5) | 70.1 (12.3) |
| >180 mg/dL | 29.7 (14.4) | 26.3 (14.4) | 25.4 (16.1) | 27.9 (13.2) |
| ≥250 mg/dL | 8.0 (7.5) | 3.6 (3.7) | 4.9 (6.3) | 6.7 (5.6) |
| ≥300 mg/dL | 2.0 (2.9) | 0.5 (1.1) | 0.1 (0.5) | 1.0 (2.2) |
Results are sensor glucose values, mean (standard deviation) unless otherwise indicated; SI conversion factor to convert glucose to mmol/L, multiply by 0.0555.
a
Initial 24 adult subjects enrolled received 80% meal bolus; all subjects enrolled subsequently received 100% meal bolus.