Table 5.

Medication use and perinatal outcomes in women diagnosed with GDM at less than 24 weeks compared to ≥24 weeks treated with glyburide

Measure	Glyburide Treatment Before IPTW			Glyburide Treatment After IPTW
	<24 weeks (n=107)	≥24 weeks (n=676)		<24 weeks (n=82)	≥24 weeks (n=619)
	n (%)	n (%)	p	Percent	Percent	p
Macrosomia	16 (15.0%)	54 (8.0%)	0.02	18.8%	9.0%	0.04
Hypertensive disorders of pregnancy	22 (20.6%)	110 (16.3%)	0.3	13.1%	17.8%	0.3
Preterm birth	26 (24.5%)	86 (12.7%)	0.001	21.3%	13.9%	0.2
Neonatal composite	32 (30.2%)	132 (19.6%)	0.01	23.6%	21.1%	0.7
Birth defects	3 (2.9%)	8 (1.2%)	0.2 (F)	3.5%	1.3%	0.3

All variables presented as mean (± standard deviation), median (interquartile range), or n (percent). IPTW (inverse probability of treatment weighting).