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Calibrationless multi-echo gradient-echo reconstruction at R=4-fold pseudo-random acceleration. Single-contrast calibrationless LORAKS yielded 4.2% error with underestimation in the R2* parameter map (yellow arrow). This is likely caused by the signal drop in the early echoes as can be better seen in the error maps. Joint calibrationless LORAKS had an improved RMSE performance of 3.1%, and mitigated the signal dropout problem in both the individual echoes and the estimated parameter map.
