Table 3.

Results of two crossed-random linear mixed models for analyzing longitudinal change in (a) cortical thickness and (b) volume.

(a)
Cortical thickness	Estimate	SE	df	t	Pr(>|t|)	Confidence Interval
						2.50%	97.50%
(Intercept)	200.59	12.12	19.22	16.55	<0.001	178.04	228.18
Time	−0.36	0.12	1684.91	−3.10	0.002	−0.60	−0.12
Age at baseline	−0.57	0.11	71.94	−5.21	<0.001	−0.75	−0.36
P-FIT regions	48.46	13.17	19.01	3.68	0.002	20.25	76.24
Time × P-FIT regions	−0.31	0.13	1708.95	−2.44	0.015	−0.56	−0.05

(b)
Cortical volume	Estimate	SE	df	t	Pr(>|t|)	Confidence Interval
						2.50%	97.50%
(Intercept)	73.03	26.42	18.87	2.76	0.014	24.39	133.54
Time	−0.48	0.05	1620.85	−9.74	<0.001	−0.58	−0.37
Age at baseline	−0.29	0.05	71.90	−5.44	<0.001	−0.38	−0.18
P-FIT regions	9.60	28.78	18.86	0.33	0.742	−52.71	70.15
Time × P-FIT regions	−0.12	0.05	1630.59	−2.27	0.024	−0.23	−0.01

Note: Significance level is p < 0.025 after adjusting for multiple comparisons.