Table 4.

Results for two crossed-random linear mixed models linking cognitive measures to (a) cortical thickness and (b) volume.

(a)
Cortical thickness	Estimate	SE	df	t	Pr(>|t|)	Confidence Interval
						2.50%	97.50%
(Intercept)	200.81	12.12	19.23	16.57	<0.001	178.20	228.43
Age at baseline	−0.51	0.11	72.89	−4.52	<0.001	−0.70	−0.29
Gf	0.27	0.06	1609.44	4.28	<0.001	0.15	0.39
Gc	−0.02	0.05	1519.07	−0.33	0.745	−0.11	0.08
Time	−0.33	0.11	1680.88	−2.84	0.005	−0.56	−0.09
P-FIT regions	48.46	13.17	19.00	3.68	0.002	20.26	76.24
Gf × Time	−0.02	0.01	1582.32	−1.90	0.058	−0.04	0.00
Gc × Time	−0.04	0.01	1565.86	−4.44	<0.001	−0.05	−0.02
Time × P-FIT regions	−0.31	0.12	1702.54	−2.47	0.014	−0.56	−0.05

(b)
Cortical volume	Estimate	SE	df	t	Pr(>|t|)	Confidence Interval
						2.50%	97.50%
(Intercept)	73.02	26.42	19.16	2.76	0.012	24.38	133.52
Age at baseline	−0.28	0.05	73.39	−5.25	<0.001	−0.38	−0.17
Gf	−0.03	0.03	1627.32	−1.14	0.255	−0.08	0.02
Gc	0.01	0.02	1596.56	0.68	0.498	−0.03	0.05
Time	−0.49	0.05	1620.44	−10.08	<0.001	−0.59	−0.38
P-FIT regions	9.60	28.78	19.15	0.33	0.742	−52.71	70.15
Gf × Time	0.02	0.00	1585.81	5.20	<0.001	0.01	0.03
Gc × Time	−0.02	0.00	1572.30	−6.51	<0.001	−0.03	−0.02
Time × P-FIT regions	−0.12	0.05	1628.47	−2.31	0.021	−0.23	−0.02

Note: Significance level is p < 0.025 after adjusting for multiple comparisons.