Table 2.
Characteristic |
Healthy subjects (n = 50) |
Patients with COPD (n = 28) |
Mechanically ventilated patients (n = 12) |
---|---|---|---|
Age, years | 48 ± 3 | 68 ± 1 | 64 ± 4 |
BMI, kg/m2 | 25.0 ± 0.4 | 25.4 ± 0.7 | 27.4 ± 1.8 |
FEV1, L (% predicted) |
3.8 ± 0.1 (105 ± 2) |
1.1 ± 0.1 (37 ± 3) |
— |
FVC, L (% predicted) |
4.8 ± 0.1 (103 ± 2) |
3.1 ± 0.1 (73 ± 3) |
— |
FEV1/FVC, % | 80 ± 1 | 37 ± 2 | — |
Total lung capacity, L (% predicted) |
— | 8.5 ± 0.3 (122 ± 4) |
— |
Residual volume, L (% predicted) |
— | 5.2 ± 0.3 (202± 14) |
— |
DL/VA, ml/min/mm Hg/L (% predicted) | — | 2.1 ± 0.2 (54 ± 4) |
— |
pH | — | 7.43 ± 0.01 | — |
PaCO2, mmHg | — | 41 ± 1 | — |
PaO2, mmHg | — | 72 ± 2 | — |
Definition of abbreviations: BMI = body mass index, FEV1 = forced expired volume in one second, FVC = forced vital capacity, DL/VA = specific diffusing capacity, PaCO2 = partial pressure of arterial carbon dioxide, PaO2 = partial pressure of arterial oxygen. Values are means ± SE.