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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Muscle Nerve. 2018 Jan 8;57(5):814–820. doi: 10.1002/mus.26025

Figure 4. NT-1654 treatment attenuates the reduction of muscle fiber diameter in EAMG rats.

Figure 4

(A) Representative hematoxylin-eosin–stained muscle cross-sections (10x magnification) of the tibialis anterior muscle show muscle fibers of healthy control, EAMG + vehicle, EAMG + NT-1654 (2 mg/kg), and EAMG + NT-1654 (6 mg/kg) rats at day 49 after immunization. Scale bar: 50 μm. (B) Summarized results of muscle fiber size distribution show attenuated reduction of muscle fiber diameter in EAMG rats after NT-1654 treatment. Values represent relative numbers of fibers in a given diameter class. Data are expressed as mean ± s.e.m.; n= 6 rats per group; **p<0.01.