Fig. 6.

Choroidal Vessels Displaced toward Bruch’s Membrane in a Treatment-Naïve Eye with Multi-lobular Geographic Atrophy (GA). A. OCT angiography (OCTA) of choriocapillaris and cross-sectional OCT with segmentation boundary lines. In the area of GA, choroidal vessels are located in the same plane as is the choriocapillaris in areas outside GA. B. OCTA of outer retina (with suppression of projection artifact) and cross-sectional OCT. En face outer retina image shows flow signal that could be misinterpreted as choroidal neovascularization. The outer segmentation boundary on cross-section (red line) is artifactually displaced deeper into the superficial choroid in areas of retinal pigment epithelium (RPE) loss (yellow arrow). C. En face structural OCT slab of the choroid used to select the area of RPE atrophy. White arrow on cross-section shows the more posterior location of choroidal vessels in areas with no RPE atrophy. D. Pseudo-colored OCTA of choriocapillaris and cross-sectional OCT with red flow overlay. Pseudo-coloring confirms that flow signal related to outer retinal flow abnormalities is due normal choroidal vessels displaced anteriorly in GA.