Table 2.
Unadjusted Change in Functional Measures in Community and Clinic Arms at 3 and 6 months
| Outcomes | Community arm | Clinic arm | All | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Change from baseline | No. | Mean (SD) | P value* | Effect size | No. | Mean (SD) | P value* | Effect size | No. | Mean (SD) | P value* | Effect size | P value† |
| 5XSTS (s)‡ | |||||||||||||
| 3 Months | 35 | −4.53 (6.78) | <0.001 | 0.67 | 32 | −5.20 (17.53) | 0.10 | 0.30 | 67 | −4.85 (12.97) | 0.003 | 0.37 | 0.67 |
| 6 Months | 32 | −4.18 (6.45) | 0.001 | 0.65 | 30 | −6.43 (14.11) | 0.02 | 0.46 | 62 | −5.27 (10.82) | <0.001 | 0.49 | 0.57 |
| 6 MW (ft)§ǁ | |||||||||||||
| 6 Months | 34 | 20.0 (291.9) | 0.69 | 0.07 | 31 | 193.9 (429.0) | 0.02 | 0.45 | 65 | 103.0 (371.3) | 0.03 | 0.28 | 0.08 |
| Borg Effort§¶ | |||||||||||||
| 6 Months | 34 | −0.21 (3.60) | 0.74 | 0.06 | 29 | −1.76 (4.19) | 0.03 | 0.42 | 63 | −0.92 (3.93) | 0.07 | 0.23 | 0.18 |
| 50FtSW (s)‡ | |||||||||||||
| 3 Months | 36 | −1.58 (5.55) | 0.10 | 0.28 | 33 | −1.22 (4.29) | 0.11 | 0.28 | 69 | −1.41 (4.95) | 0.02 | 0.28 | 0.90 |
| 6 Months | 36 | −1.32 (7.16) | 0.28 | 0.18 | 31 | −1.42 (4.85) | 0.11 | 0.29 | 67 | −1.37 (6.15) | 0.07 | 0.22 | 0.88 |
| SF-12 PCS§# | |||||||||||||
| 6 Months | 35 | 2.20 (8.56) | 0.14 | 0.26 | 30 | 6.76 (9.99) | 0.001 | 0.68 | 65 | 4.31 (9.45) | 0.001 | 0.46 | 0.06 |
| PSFS** | |||||||||||||
| 3 Months | 36 | 1.07 (1.95) | 0.002 | 0.55 | 32 | 1.04 (1.66) | 0.001 | 0.63 | 68 | 1.05 (1.80) | <0.001 | 0.58 | 0.75 |
| 6 Months | 36 | 1.64 (2.28) | <0.001 | 0.72 | 30 | 1.65 (1.77) | <0.001 | 0.93 | 66 | 1.64 (2.05) | <0.001 | 0.80 | 0.86 |
| SDMT†† | |||||||||||||
| 3 Months | 36 | 4.19 (6.61) | <0.001 | 0.63 | 32 | 6.84 (10.0) | <0.001 | 0.68 | 68 | 5.44 (8.42) | <0.001 | 0.65 | 0.19 |
| 6 Months | 36 | 4.61 (8.67) | 0.003 | 0.53 | 30 | 7.37 (8.94) | <0.001 | 0.82 | 66 | 5.86 (8.84) | <0.001 | 0.66 | 0.10 |
Abbreviations: 5XSTS Five Times Sit-to-Stand, 6 MW 6-Min Walk, Borg Effort Borg Perceived Effort Test, 50FtSW 50-ft Speed Walk, SF-12 PCS 12-Item Short-Form Physical Component Summary, PSFS Patient-Specific Functional Scale, SDMT Symbol–Digit Modalities Test
*One-sample t test was used for examining the changes for clinic and for community, separately
†Mann–Whitney U test was used for examining the differences between two arms
‡Lower scores indicate faster completion of test and better physical function
§Measures only assessed at baseline and 6 months
ǁHigher scores indicate ability to walk farther within time frame and better physical function
¶Modified score range is 0–10. Higher scores indicate greater effort to accomplish task
#12-Item Short-Form Physical Component Summary. Scores range from 0 to 100. Higher scores indicate better physical performance and capacity
**Patient-Specific Functional Scale: Scores range from 0 to 10. Higher scores indicate better activity performance
††Symbol–Digit Modalities Test: Scores range from 0 to 110. Higher scores indicate better cognitive function