Table 1.

Thermodynamic parameters measured at 37 °C obtained from fitting the ITC data to “one-set-of-identical-binding-sites” model.

CPP	ΔH (kJ/mol)	Binding stoichiometry (n)
PEN	−0.34, −0.33	65, 63
PENRhB	−0.46, −0.46	36, 38
PENTAMRA	−0.39, −0.37	41, 41
PENPBA*	−1.50 ± 0.08	38 ± 1
PENNBD*	−0.64 ± 0.07	48 ± 5
PENMCA	−0.83, −0.87	37, 38

*Triplicate measurements listed as mean ± standard deviation. All other compounds were measured in duplicate, and listed as values for single measurements.