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. 2018 Apr 20;8:6316. doi: 10.1038/s41598-018-24752-x

Table 1.

Analysis of the metastasis rate and survival time of LLC-1 xenograft mice.

All cases (%) Metastasis (%)a p valueb,c
Total 31 (100%) 5 (16.1%)
Water type 0.048
DI 17 (54.8%) 5 (100%)
PIA 14 (45.1%) 0 (0%)
Survival days (mean ± SD)
Total 6.34 ± 0.41
Treatment
DI 4.62 ± 0.71
DI + Cs 6.38 ± 0.61 0.081
PIA 6.57 ± 0.66 0.118
PIA + Cs 8.01 ± 0.77 0.009

aLung metastasis was examined by gross observation of the whole lung.

bp values were analyzed by a two-tailed Fisher test.

cp values were analyzed by a log-rank test compared to the DI (DI water alone, n = 9) group and DI + Cs (DI water plus cisplatin, n = 8), PIA (PIA water, n = 7), or PIA + Cs (PIA water plus cisplatin, n = 7) group.