Fig. 3.

Activity of factor VIII (FVIII), von Willebrand factor antigen (VWF:Ag), and von Willebrand factor activity (VWF:RCo) during the perioperative period.

We could confirm that the highest activity level of FVIII increased to 200%, that of VWF:Ag to 265%, and that of VWF:RCo to 130%. The postoperative activity of FVIII, VWF:Ag, and VWF:RCo increased and peaked on the first postoperative day, and the infusion of FVIII/VWF concentrate was stopped; activity levels dropped continuously until discharge on day 12.