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. 2018 Apr 20;15:118. doi: 10.1186/s12974-018-1155-z

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Knockdown of BLVRA aggravated GMH-induced inflammation. a Western blot analysis of BLVRA and inflammatory cytokine expression in BLVRA-treated and BLVRA-knockdown splenic tissues; representative blots are shown. b Quantitative analysis of BLVRA and inflammatory cytokine expression in BLVRA-treated and BLVRA-knockdown splenic tissues. c Western blot analysis of inflammatory cytokine expression in BLVRA-treated brain tissues; representative blots are shown. d Quantitative analysis of inflammatory cytokine expression in BLVRA-treated brain tissues. Values are expressed as mean ± SD. ^*P < 0.05 compared with sham, ^#P < 0.05 compared with GMH + vehicle. ^&P < 0.05 compared with GMH + BLVRA. ^%P < 0.05 compared with GMH + scrambled siRNA. N = 6 each group