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. 2017 Dec 19;26(3):834–844. doi: 10.1016/j.ymthe.2017.12.014

Figure 5.

Figure 5

Administration of PEG-CBS Rescues Facial Alopecia in I278T Mice

Headshots of representative mice from each study group are shown. (A) Untreated negative controls at 19 and 34 weeks of age (W19, W34). (B) Untreated positive controls with fully developed facial alopecia at age of 24 and 38 weeks. (C) Alopecia is prevented by continuous treatment of I278T mice from weaning age onward. (D) Fully developed facial alopecia is reversed by instigating continuous PEG-CBS treatment at 27 weeks.