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. 2018 Jan 10;26(3):793–800. doi: 10.1016/j.ymthe.2018.01.002

Figure 6.

Figure 6

Diminished Cerebral Cortical Astrogliosis in iNat8l-V-Treated AspaNur7/Nur7 Mice

Low magnification cerebral cortical images, immunostained for GFAP and Iba1 with higher magnifications of the boxed areas, are shown from a 3-month-old untreated Aspa+/+ mouse, a 3-month-old untreated AspaNur7/Nur7 mouse, and a P1 iNat8l-V treated 3-month-old AspaNur7/Nur7 mouse. Note prominent astrogliosis in the untreated 3-month-old AspaNur7/Nur7 mouse, with less prominent astrogliosis in the P1 iNat8l-V treated 3-month-old AspaNur7/Nur7 mouse. Scale bars, 100 μm (upper panels) and 25 μm (lower panels).