Fig. 4.

Protein turnover is accelerated by EE experience. (A) Plot indicates the ranked turnover ratios of synaptosomal and cytosolic proteins from control mice and mice that underwent 3 d of EE exposure. EE exposure resulted in an almost uniform increase in protein turnover that was statistically significant (P < 0.001, Student’s t test). Data obtained from four control mice and four EE mice. (B) Plot indicates the ranked protein turnover from control mice and the paired values obtained from EE mice. The spread indicates that certain proteins from synaptosomal and cytosolic fractions were disproportionally affected by EE exposure. Data obtained from four control mice and four EE mice.