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. 2018 Apr 2;115(16):E3858–E3861. doi: 10.1073/pnas.1804573115

Fig. 1.

Fig. 1.

The effects of Rgs5 on cardiac hypertrophy. (A and B) Gross heart and WGA-FITC and HE staining of sham and AB mice at 4 wk after surgery in TG and WT mice (A) and in Rgs5−/− and Rgs5+/+ mice (B). Analysis of hypertrophic markers in TG and WT mice (C) and in Rgs5−/− and Rgs5+/+ mice (D). Total RNA was isolated from hearts of mice of the indicated groups, and expression of transcripts for ANP, BNP, and β-MHC induced by AB were determined by real-time PCR analysis. Data represent typical results of three to four different experiments as mean ± SEM (n = 4–11 mice per group). *P < 0.01 for WT/sham; #P < 0.01 for WT/AB after AB.