Table 3. Cytogenetic abnormalities.
Cytogenetic abnormalities in patients with Multiple Myeloma and auto-HCT with and without CKS1B gene amplification.
| Cytogenetic Abnormality
|
Group (N, %)
|
|
|---|---|---|
| Control (58, 100) | CKS1B (58, 100) | |
| Complex (≥3 abnormalities) | 12 (21) | 25 (43) |
| monosomy 13 / deletion 13q | 10 (17) | 27 (47) |
| IGH gene rearrangement, | 8 (14) | 8 (14) |
| t(11;14) | 10 (17) | 3 (5) |
| Hyperdiploidy | 2(3) | 7 (12) |
| Pseudodiploidy | 4 (7) | 5 (9) |
| Del etion17p | 0 (0) | 7 (12) |
| Trisomy 11 | 3 (5) | 3 (5) |
| t(14;16) | 0 (0) | 3 (5) |
| t(4;14) | 0 (0) | 3 (5) |
| Hypodiploidy | 3 (5) | 1 (2) |
| Trisomy 9 | 1 (2) | 1 (2) |
| add(X)(p22.1) | 1 (2) | 0 (0) |
| Trisomy 13 | 1 (2) | 0 (0) |
| Deletion 14 | 1 (2) | 0 (0) |
| del(2)(q31) | 0 (0) | 1 (2) |
| inv(9)(p12q13) | 0 (0) | 1 (2) |
| Trisomy 5 | 1 (2) | 1 (2) |
| Tetrasomy 11 | 1 (2) | 0 (0) |
| del(15)(q21) | 0 (0) | 1 (2) |
| t(5;10)(q31;p15) | 0 (0) | 1 (2) |
| Hypertriploidy | 0 (0) | 1 (2) |
| Hypotriploidy | 0 (0) | 1 (2) |
| Hypotetraploidy | 1 (2) | 1 (2) |
| ins(5;2) | 1 (2) | 0 (0) |
| Deletion 16q | 1 (2) | 0 (0) |
| del(X)(q22) | 1 (2) | 0 (0) |
| del(11)(q23) | 1 (2) | 0 (0) |
| Trisomy 12 | 0 (0) | 1 (2) |
| del(9)(q12) | 1 (2) | 0 (0) |
| Trisomy 3 | 1 (2) | 1 (2) |