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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Virology. 2018 Mar 15;518:221–231. doi: 10.1016/j.virol.2018.02.023

Figure 1. Effect of adenovirus infection on MRN protein levels.

Figure 1

(A) Western blot analysis of Mre11, Rad50, and Nbs1 using infected cell lysates. U2OS cells were infected with serotypes from subgroups A-E and harvested at 48 and 72 hours post-infection (hpi). Subgroups are indicated in parentheses. Viral DBP confirms infection for all serotypes except Ad12. (B) Western blot analysis of Rad50 during Ad35 and Ad5 infection in the presence of the proteasome inhibitor MG132. Cells were treated with 20 uM MG132 or equal volume DMSO 8 hpi and harvested at the indicated time points. MG132 and DMSO were refreshed every 24 hours.