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. 2018 Apr 22;9:33. doi: 10.1186/s40104-018-0249-x

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Simplified scheme of intestinal N metabolism and the target sites of manipulation strategies for reducing ruminal NC degradation that have shown effectiveness in vivo or in vitro (according to [6, 22, 86, 87, 102, 138, 151, 155, 156, 160, 166, 168, 202, 208, 218]). ¹This NC can also be supplied with the feed; ²Urea is partly excreted with urine