. Author manuscript; available in PMC: 2018 Apr 22.

Published in final edited form as: J Gerontol A Biol Sci Med Sci. 2008 Aug;63(8):848–854. doi: 10.1093/gerona/63.8.848

Table 2.

Linear Regression β Values and 95% Confidence Intervals (95% CI) of White Matter Lesions (WMLs) and Leisure Activity and Cognitive Function for Total Sample (N = 1787)

Main Effects	Memory β (95% CI)		Speed of Processing β (95% CI)		Executive Function β (95% CI)
Main Effects	Model 1	Model 2	Model 1	Model 2	Model 1	Model 2
WML load (high vs low)	−0.06 (−0.15, 0.02)	−0.09 (0.18, 0.01)	−0.06^* (−0.13, −0.01)	−0.09^* (−0.17, −0.02)	−0.05 (−0.12, 0.02)	−0.05 (−0.12, 0.02)
Leisure activity (high vs low)	0.20^† (0.11, 0.29)	0.17^‡ (0.07, 0.28)	0.37^† (0.29, 0.45)	0.33^† (0.24, 0.42)	0.23^† (0.15, 0.29)	0.23^† (0.14, 0.31)
Interaction of WML × Leisure activity	–	0.11 (−0.07, .30)	–	0.15^* (0.01, 0.30)	–	0.02 (−0.17) 0.12,

Notes: Model 1 = main effects model Adjusted for age, education, sex, depression, body mass index (BMI), myocardial infarction (MI), total cholesterol, apolipoprotein E (ApoE) genotype, hypertension, and smoking status. Model 2 = high WML × High Leisure activity interaction term included. Adjusted for age, education, gender, depression, BMI, MI, total cholesterol, ApoE genotype, hypertension, smoking status, and cerebral infarcts.

p < .05;

^†

p < .01;

^‡

p < .01.