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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Graefes Arch Clin Exp Ophthalmol. 2018 Mar 5;256(5):935–949. doi: 10.1007/s00417-018-3905-0

Table 2.

KEGG pathways unique to PCI vs. ShamN group. The list was compiled by comparing significantly affected pathways in PCI vs. ShamN to ShamI vs. ShamN and keeping only the ones unique for the former. No pathways were unique for the latter. The list of affected pathways was generated by iPathwayGuide. Pathways with FDR value ≤ .05 in PCI vs. ShamN and Q value > .05 in ShamI vs. ShamN are shown. Biologically related pathways are bolded.

PCI vs. ShamN Unique Pathways
Pathway name p-value
MAPK signaling pathway 1.05E-06
Regulation of actin cytoskeleton 2.66E-05
Apoptosis 6.87E-05
Measles 7.73E-05
Jak-STAT signaling pathway 8.69E-05
Focal adhesion 1.75E-04
Hepatitis B 1.88E-04
PI3K-Akt signaling pathway 2.48E-04
Non-alcoholic fatty liver disease (NAFLD) 5.06E-04
Insulin resistance 8.77E-04
Adipocytokine signaling pathway 9.10E-04
Pathways in cancer * 9.84E-04
Cytosolic DNA-sensing pathway 0.002
Amyotrophic lateral sclerosis (ALS) 0.003
HIF-1 signaling pathway 0.005
Viral carcinogenesis 0.008
Epstein-Barr virus infection 0.008
Rap1 signaling pathway 0.008
T cell receptor signaling pathway 0.01
p53 signaling pathway 0.013
Platelet activation 0.017
MicroRNAs in cancer * 0.019
Adherens junction * 0.029
Small cell lung cancer 0.034
RIG-I-like receptor signaling pathway 0.047
Arginine and proline metabolism * 0.047
Bladder cancer 0.048
Cell cycle 0.049