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. 2018 Apr 16;12:102. doi: 10.3389/fncel.2018.00102

FIGURE 2.

FIGURE 2

Two examples of hippocampal neuron responses to noise and tone stimuli. (A,B) Responses of CA3 neurons to noise bursts alone (A) and to noise and tone bursts (B). Upper left panel, PSTH displaying the responses to noise at 90 dB SPL, extracted from the amplitude scans. Lower left panel, PSTH displaying the responses to all test tones at 90 dB SPL extracted from the responses to the frequency-amplitude scans displayed on the right color map, which depicts instantaneous discharge rates. Inset: 20 randomly selected superimposed spike waveforms. Scale: 60 pA, 0.5 ms. (C) A small number of neurons in the EC (n = 5), CA3 (n = 2), and CA1 (n = 3) that can respond to tone bursts. Spike rate-intensity functions of 10 neurons in response to both noise (red) and tone (black) stimulation. (D) Spike rate-frequency functions of the 10 neurons, individual (gray lines) and mean ± SEM (black line). The spike rate at each frequency was based on the responses at all intensities.