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. 2018 Apr 16;9:158. doi: 10.3389/fendo.2018.00158

Table 1.

Clinicopathological features of patients in discovery and validation phase.

Clinicopathological features Discovery phase
Validation phase
Papillary thyroid carcinoma (PTC) LNM-P n(%) PTC LNN n(%) PTC LNM-P n(%) PTC LNN n(%)
Gender
Male 0 (0) 0 (0) 4 (57.1) 2 (50)
Female 5 (100) 5 (100) 3 (42.9) 2 (50)
Ethnic
Malay 3 (60) 4 (80) 6 (85.7) 2 (50)
Chinese 2 (40) 1 (20) 1 (14.3) 1 (25)
Indian 0 (0) 0 (0) 0 (0) 1 (25)
Age at diagnosis, year
≥45 years old 4 (80) 4 (80) 5 (71.4) 2 (50)
<45 years old 1 (20) 1 (20) 2 (28.6) 2 (50)
Mean 51.6 47.4 43.4 41.5
Tumor location
Right lobule 3 (60) 3 (60) 4 (57.1) 1 (25)
Left lobule 1 (20) 1 (20) 3 (42.9) 3 (75)
Isthmus 1 (20) 1 (20) 0 (0) 0 (0)
Tumor size (cm)
≤1 0 (0) 2 (40) 0 (0) 1 (25)
>1 5 (100) 3 (60) 7 (100) 3 (75)
BRAF V600E mutation
Positive 5 (100) 0 (0) 6 (85.7) 2 (50)
Negative 0 (0) 5 (100) 1 (14.3) 2 (50)