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Ratio of circulating Glu-osteocalcin (Glu-OC) and Gla-osteocalcin (Gla-OC) measured by ELISA in pseudoxanthoma elasticum (PXE) patients, in heterozygous ABCC6 mutation carriers (ABCC6 carriers) and in non-carriers after 1 and 6 weeks post-phytomenadione administration. Data are expressed as percentage reduction (means value ± SD) compared to baseline (p < 0.05 along time for the three groups).
