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. 2018 Mar 1;7(4):1394–1403. doi: 10.1002/cam4.1326

Figure 2.

Figure 2

Overexpression of miR‐641 results erlotinib resistance in NSCLC cells. (A) Transfection of miR‐641 mimics significantly increased the miR‐641 level in PC‐9 cells. After 72 h of transfection, cells were subjected to qRT‐PCR analysis. (B) Cell viability assay shows that overexpression of miR‐641 can protect PC‐9 cells from erlotinib (Er)‐induced cell death. (C) Clonogenic assay shows that overexpression of miR‐641 abolished erlotinib‐induced colony formation inhibition of PC‐9 cells. (D) Flow cytometric analysis show that overexpression of miR‐641 protects PC‐9 cells from erlotinib‐induced apoptosis. *P < 0.05; **P < 0.01; ***P < 0.001.