Table 4.
Outcomes of included studies investigating patients with ischemic stroke caused by a “tandem lesions” who underwent acute mechanical thrombectomy with or without emergency extracranial carotid stenting, who received periprocedural antithrombotic drugs as protocol-based care.
| Reference | sICH, n/N (%) | Mortality, n/N (%) | mRS (0–2), n/N (%) |
|---|---|---|---|
| Behme et al. (21) | 15/170 (9%)a | 32/170 (19%) | 62/170 (36%) |
| Cohen et al. (23) | 0/24 (0%)b | 2/24 (8%) | 13/24 (54%) |
| Heck and Brown (25) | 5/23 (2%)c | 9/23 (39%) | 12/23 (52%) |
| Lockau et al. (28) | 4/37 (11%)d | 7/37 (19%) | 17/37 (46%) |
| Marnat et al. (29) | 1/20 (5%)a | 0/20 (0%) | 14/20 (70%) |
| Maurer et al. (30) | 5/43 (12%)e | 9/43 (21%) | 14/43 (33%) |
| Rangel-Castilla et al. (34) | 2/45 (4%)f | 5/45 (11%) | 22/45 (49%) |
| Stampfl et al. (35) | 4/24 (17%)a | 4/24 (17%) | 7/24 (29%) |
mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; sICH, symptomatic intracranial hemorrhage.
aECASS-II definition (42).
bIntracranial hemorrhage resulting in NIHSS increase of ≥4 within 36 h.
cSITS-MOST definition (41).
dIntracranial hemorrhage resulting in NIHSS increase of >4.
eNo specific definition of sICH given.
fIntracranial hemorrhage resulting in NIHSS increase of ≥4 or death.