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. 2018 Apr 16;9:747. doi: 10.3389/fimmu.2018.00747

Figure 5.

Figure 5

Levels of Streptococcus mitis- and Streptococcus pneumoniae-reactive IgG antibodies isolated from S. pneumoniae 6B-inoculated adults. Pre- and post-inoculation plasma samples were collected from 13 individuals inoculated with S. pneumoniae 6B. Serially diluted plasma samples were added to wells in duplicate. The OD values were converted to titers, with a cutoff value of 0.20 (see legend to Figure 2). The levels of IgG antibody titers against S. mitis and S. pneumoniae strains are shown. OD values are shown for each subject at pre- and post-challenge time points. (A) Pre- and post-challenge IgG levels to S. mitis and S. pneumoniae 6B. (B) Pre- and post-challenge IgG levels to S. mitis and S. pneumoniae 6B linked for each subject. Wilcoxon Signed Rank Test, *p < 0.05; ***p < 0.001. Abbreviations: PRE, pre-inoculation sera; POST, post-inoculation sera.