. 2014 May 1;31(9):834–845. doi: 10.1089/neu.2013.3155

Table 2.

Cancellous Histomorphometric Characteristics at the Proximal Tibial Metaphysis after Sham Surgery (T9 Laminectomy) or Moderate/Severe (250 Kdyne) Spinal Cord Injury Alone or in Combination with a Low or High Dose of Testosterone-Enanthate

	SHAM (a)	SCI (b)	SCI+LowTE (c)	SCI+HighTE (d)
Cn.BV/TV, %	4.6±2.6^{b^*}	0.8±0.5^{a^,c^,d^*}	3.5±1.4^{b^*}	4.6±2.6^{b^*}
Tb.N, #/mm	3.7±1.9^{b^*}	0.9±0.6^{a^,c^,d^*}	3.3±1.3^{b^*}	4.1±2.1^{b^*}
Tb.Wi, μm	14.6±3.2^b	10.7±3.0^a,d	12.5±1.2	13.0±1.4^b
Tb.Sp, μm	463±566^{b^*}	1520±911^{a^,c^,d^*}	384±300^{b^*}	322±224^{b^*}
Oc.S/BS, %	4.2±1.5	6.3±3.6^d	4.2±1.1	3.2±0.7^b
Ob.S/BS, %	19.2±4.6	16.0±8.4	14.5±4.3	14.1±6.6
OS/BS, %	16.1±3.6	13.5±7.0	12.2±4.4	11.8±5.3
MS/BS, %	13.5±4.2^{b^,c^}	2.6±1.6^{a^,c^,d}	5.7±2.3^{a^,b^}	8.9±6.5^b
MAR, μm/day	1.2±0.5^b	0.6±0.4^a,d	0.8±0.3	1.2±0.4^b
BFR/BS (dL), μm³/μm²/day	16.6±7.8^{b^,c^}	1.2±0.9^{a^,c^,d^*}	4.9±3.3^{a^,b^}	11.4±11.7^{b^*}

Values are means±standard deviation of n=8–9/group. Letters a–d indicate differences from respectively labeled groups at p<0.05 or ^* p<0.01 (a=vs. SHAM, b=vs. SCI, c=vs. SCI+LowTE, d=vs. SCI+HighTE). SCI, spinal cord injury; SCI+LowTE, spinal cord injury plus low-dose testosterone-enanthate; SCI+HighTE, spinal cord injury plus high-dose testosterone-enanthate. Cn.BV/TV, cancellous bone volume; Tb.N, trabecular number, Tb.Wi, trabecular width; Tb.Sp, trabecular separation; Oc.S/BS, osteoclast surface; Ob.S/BS, osteoblast surface; OS/BS, osteoid surface; MS/BS, mineralizing surface; MAR, mineral apposition rate, BFR/BS, bone formation rate/bone surface.