Table 3.
Genotypes of patient samples in relation to clinical status.
| Total (N = 141) | By type of HBV infection |
p Value | Crude OR of being IC (95% CI) | ||
|---|---|---|---|---|---|
| IC (N = 92) | HCC (N = 49) | ||||
| IFNARPPs genotypes | |||||
| SNP −568*, n (%) | 0.313 | ||||
| CC | 54 (42.2) | 41 (44.6) | 13 (36.1) | 1 | |
| CG | 63 (49.2) | 42 (45.7) | 21 (58.3) | 1.57 (0.65, 3.90) | |
| GG | 11 (8.6) | 9 (9.8) | 2 (5.6) | 0.70 (0.06, 4.07) | |
| SNP −408/−3, n (%) | 0.094 | ||||
| CC | 62 (44.0) | 41 (44.6) | 21 (42.9) | 1 | |
| CT | 71 (50.4) | 43 (46.7) | 28 (57.1) | 1.26 (0.59, 2.75) | |
| TT | 8 (5.7) | 8 (8.7) | 0 (0.0) | NA | |
| VNTR −77(GT)n, n (%) | |||||
| ≤8/≤8 | 63 (44.7) | 48 (52.2) | 15 (30.6) | 1 | |
| ≤8/>8 | 63 (44.7) | 36 (39.1) | 27 (55.1) | p < 0.05 | 0.41 (0.19, 0.90) |
| >8/>8 | 15 (10.6) | 8 (8.7) | 7 (14.3) | 0.36 (0.11, 1.14) | |
| ≤8/≤8 | 63 (44.7) | 48 (52.2) | 15 (30.6) | 1 | |
| ≤8/>8 or >8/>8 | 78 (55.3) | 44 (47.8) | 34 (69.4) | p < 0.05 | 0.40 (0.19, 0.84) |
Statistically significant associations in bold.
IC, inactive carrier; HCC, hepatocellular carcinoma.
*Genotype available only for 118 samples (92 for IC and 36 for HCC).