Table 3.
Subgroup analysis of NIHSS score based on treatment duration, RIPostC protocol, and stroke history
| Subgroup | Number of study, n | Number of patients, n | Estimated effect (MD, 95% CI) | I2 (%) | Analysis model | Z | P |
|---|---|---|---|---|---|---|---|
| Treatment duration (days) | |||||||
| ≤14 | 5 | 626 | 2.38 (−4.52, −0.24) | 98 | Random | 2.18 | 0.030 |
| >14 | 4 | 350 | 2.88 (−5.11, −0.65) | 92 | Random | 2.54 | 0.010 |
| RIPostC protocol (total duration, min) | |||||||
| <90 | 5 | 508 | 2.26 (−4.45, −0.07) | 98 | Random | 2.02 | 0.040 |
| ≥90 | 4 | 468 | 3.01 (−5.09, −0.94) | 92 | Random | 2.85 | 0.004 |
| Stroke history (days) | |||||||
| ≥14 | 7 | 756 | 2.25 (−3.91, −0.59) | 97 | Random | 2.66 | 0.008 |
| >14 | 2 | 220 | 3.77 (−7.41, −0.13) | 91 | Random | 2.03 | 0.040 |
NIHSS: National Institute of Health stroke scale; RIPostC: Remote ischemic postconditioning; MD: Mean difference; CI: Confidence interval.