Table 3.
Univariate and Multivariate Cox Proportional Hazards for Predictors of Renal Impairment (With Baseline Covariates) (n = 921)
Variable | Univariate Model Unadjusted HR (95% CI) | P Value | Multivariate Model Adjusted HR (95% CI) |
P Value |
---|---|---|---|---|
Age, per 10 y | 1.76 (1.50–2.05) | <.001 | 1.85 (1.56–2.20) | <.001 |
Female sex | 0.83 (0.57–1.21) | .326 | 1.15 (0.78–1.72) | .483 |
BMI, kg/m2 | ||||
≥18.5 | 1 | 1 | ||
<18.5 | 1.53 (1.01–2.29) | .043 | 1.25 (0.81–1.92) | .320 |
CD4 count, cells/mm3 | ||||
≥200 | 1 | |||
<200 | 2.00 (1.38–2.90) | <.001 | 2.05 (1.36–3.09) | .001 |
Hypertension | ||||
No | 1 | 1 | ||
Yes | 1.65 (0.99–2.76) | .057 | 1.43 (0.83–2.45) | .193 |
WHO stage | ||||
I or II | 1 | 1 | ||
III or IV | 1.83 (1.27–2.63) | .001 | 1.47 (0.97–2.25) | .072 |
Tuberculosis diagnosis | ||||
No | 1 | 1 | ||
Yes | 0.94 (0.55–1.59) | .816 | 0.60 (0.34–1.05) | .076 |
Started ART | ||||
No | 1 | 1 | ||
Yes | 0.83 (0.40–1.70) | .601 | 0.56 (0.25–1.26) | .159 |
Abbreviations: BMI, body mass index; CI, confidence interval; HR, hazard ratio; WHO, World Health Organization.