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. 2018 Apr 18;11:2205–2216. doi: 10.2147/OTT.S156361

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© 2018 Wei et al. This work is published and licensed by Dove Medical Press Limited

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miR-488 suppressed cell migration, invasion, and EMT in RCC cells.

Notes: Cell migration (A) and cell invasion (B) were determined in 786-O and A498 cell lines transfected with miR-488 or miR-NC by Transwell assays. (C) The protein expression levels of E-cadherin, N-cadherin, and vimentin in 786-O and A498 cell lines transfected with miR-488 or miR-NC were determined by Western blot analysis. GAPDH was used as the internal control. All data are shown as mean±SD. *P<0.05; **P<0.01 vs miR-NC.

Abbreviations: EMT, epithelial-to-mesenchymal transition; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; miR-NC, miR-488 negative control; RCC, renal cell carcinoma.