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Kellgren–Lawrence grade at baseline and at Week 15
| Week 15 | Baseline
|
||||
|---|---|---|---|---|---|
| Grade 1 | Grade 2 | Grade 3 | Grade 4 | ||
| Placebo (n=176) | Grade 0 | 0 | 0 | 0 | 0 |
| Grade 1 | 9 | 0 | 1 | 0 | |
| Grade 2 | 1 | 79 | 4 | 0 | |
| Grade 3 | 0 | 4 | 67 | 0 | |
| Grade 4 | 0 | 0 | 1 | 8 | |
| No observation | 0 | 1 | 1 | 0 | |
| Duloxetine (n=178) | Grade 0 | 0 | 0 | 0 | 0 |
| Grade 1 | 12 | 2 | 0 | 0 | |
| Grade 2 | 2 | 79 | 1 | 0 | |
| Grade 3 | 0 | 2 | 67 | 0 | |
| Grade 4 | 0 | 0 | 0 | 7 | |
| No observation | 0 | 5 | 1 | 0 | |
Note: Shading indicates no change in Kellgren–Lawrence grade.
