Figure 4.

Lack of a role for LysMD3 in the control of C. rodentium and S. typhimurium infection. Littermate-matched male mice were infected with 1e9 CFU C. rodentium on day 0, and morbidity (A) and fecal shedding (B) were evaluated. At 8 DPI, colons were evaluated for inflammation (C and D). Each dot represents the histology score for one mouse. E and F, mice were infected with 1e8 CFU S. Typhimurium. At 2 DPI, colons were harvested and evaluated for inflammation. All experiments were performed in duplicate using littermate-matched male mice from the LysMD3 EN mouse line.