Table 3. Diagnostic Scoring Aid (DSA) results.
Profiles of 30 patients attending a specialist clinic with memory secondary to neurological disorders (ND) – this includes neurodegenerative dementias and mild cognitive impairment due to likely underlying neurodegenerative aetiology or functional memory disorder (FMD). 3a: Items rated in all encounters / 3b: Items only rated in encounters also involving an accompanying person (AP).
For a full description of the items see supplementary appendix. Some items were unratable because a particular question was not asked (eg. “who is most concerned?”).
| a | ||||||
|---|---|---|---|---|---|---|
| Item | Description* | A: Typical of ND | B: Typical of FMD | Number of ND cases categorized A/B** (n=15) | Number of FMD cases categorized A/B** (n=15) | Difference ND versus FMD (p-value) |
| 1 | Is the patient accompanied | Yes | No | 14/1 | 6/9 | p=0.003 |
| 2 | Who is most concerned? | Others | Patient themselves | 6/1 | 0/9 | p=0.0008 |
| 3 | Specific example of memory failure | No or partial / incomplete answer or offers a general / routine problem | Detailed and specific response about a recent occurrence | 11/0 | 1/11 | p<0.0001 |
| 4 | Ability to recall recent episodic memory during interaction | Patient unable to recall earlier talk | Patient able to recall earlier talk ("Like I said") | 11/3 | 0/8 | p=0.001 |
| 5 | Responding to compound questions | Unable to attend to different parts of compound questions | Can attend to different parts of compound questions | 7/1 | 3/7 | p=0.02 |
| 6 | Prevalence of "I don't know" verbal responses | Indicates recall-based problems | Response to unexpected questions | 11/1 | 1/14 | p<0.0001 |
| 7 | Patients' elaborations and length of turns | Short, 'literal' answers | Long responses, that provide extra detail | 9/6 | 0/11 | p=0.002 |
| 8 | Repetition | More frequent | Less frequent | 10/3 | 1/11 | p=0.001 |
| 9 | Production of talk | Struggle to reply to questions, communication difficulties | Able to provide answers when asked | 7/2 | 1/13 | p=0.001 |
| b | ||||||
| Item | Description* | A: Typical of ND | B: Typical of FMD | Number of ND cases categorized A/B** (n=14) | Number of FMD cases categorized A/B** (n=6) | Difference ND versus FMD (p-value) |
| 10 | Main interactional contribution/role of the AP | AP acts as patient's representative or spokesperson | AP’s role limited to confirmation checks and second opinions | 9/1 | 1/5 n = 6 | p=0.008 |
| 11 | Presence of head-turning sign (excluding verbal "I don't know" replies) | Patient defers answering to AP by turning to them | Able to answer most questions, turn for confirmation only | 10/4 | 3/3 | n. s. |
| 12 | Disagreements between patient and AP | Present | Not present | 13/1 | 2/4 | n. s. |
| 13 | Word searches | Displays 'word search' difficulties during consultation, AP provides 'missing' information | Report 'word search' difficulties in the past but does not display ‘word search’ | 3/1 | 3/3 | n. s. |
| 14 | Responding to personal questions | Evidence of difficulties answering these questions | Can answer these questions relatively easily | 6/5 | 0/6 | n. s. |