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. 2018 Apr 18;13:2365–2376. doi: 10.2147/IJN.S163206

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© 2018 Kawamoto et al. This work is published and licensed by Dove Medical Press Limited

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Characterization of GO scaffold.

Notes: (A) GO dispersing solution. (B) GO scaffold. (C) Collagen scaffold. (D, E) SEM images of GO scaffold. A wrinkled structure of GO (white arrowheads) was observed on collagen fibers of GO scaffold. (F, G) SEM images of collagen scaffold. Visible striations (yellow arrowheads) were shown on collagen fibers of untreated collagen scaffold. (H) Compressive strength of scaffolds (N=6, mean ± SD). *P<0.05. (I) WST-8 and (J) LDH activity of MC3T3E-1 cells seeded onto scaffolds (N=4, mean ± SD). Scale bars represent 1 cm (A), 3 mm (B, C), 100 μm (D, F), and 1 μm (E, G).

Abbreviations: Col, collagen; GO, graphene oxide; LDH, lactate dehydrogenase; SEM, scanning electron microscopy, WST-8, water-soluble tetrazolium salt.